Prof. Dr. Ralf Mohrmann
Prof. Dr.ret.nat. Ralf Mohrmann
| since 2018 |
Full Professorship (W2) „Neurophysiology and celular Imaging“, Otto-von-Guericke-University Magdeburg (Germany) |
|
2015-2017 |
Workgroup leader, Saarland-University (Germany) |
|
2013-2020 |
Research project leader (together with Prof. Dr. D. Bruns) in CRC 1027 „Physical Modeling of non-equilibrium processes in biological system“ |
|
2009-2016 |
Junior-Professorship (ZHMB Junior Group Physiology), Saarland-University (Germany) |
|
2006-2009 |
Postdoc at the Dept. Membrane Biophysics (Director: Prof. Dr. Erwin Neher), workgroup of PD Dr. Jakob Sørensen, MPI f. Biophysical Chemistry, Göttingen (Germany) |
| 2001-2005 |
Postdoc in the lab of Prof. Dr. Kendal Broadie, Vanderbilt University, Nashville (U.S.A.) |
|
1997-2001 |
Dissertation at the Dept. Cell Physiology (Supervisor: PD. Dr. Kurt Gottmann), Faculty of Biology, Ruhr-University Bochum (Germany) Titel: “Mechanisms and Regulation of Synaptogenesis in cultivated neocortical Neurons.“ |
|
1997 |
Diploma thesis, Dept. Cell Physiology (Prof. Dr. Hanns Hatt), Faculty of Biology, Ruhr-University Bochum (Germany) |
|
1992-1996 |
Study of Biochemistry (Diploma) at Ruhr-University Bochum (Germany) |
2021
Harb A, Vogel N, Shaib A, Becherer U, Bruns D, Mohrmann R.
Auxiliary Subunits Regulate the Dendritic Turnover of AMPA Receptors in Mouse Hippocampal Neurons
Front Mol Neurosci. 2021 Aug 23;14:728498. doi: 10.3389/fnmol.2021.728498. eCollection 2021.
2020
2019
Shaaban A, Dhara M, Frisch W, Harb A, Shaib AH, Becherer U, Bruns D, Mohrmann R.
The SNAP-25 linker supports fusion intermediates by local lipid interactions.
Elife. 2019 Mar 18;8:e41720. doi: 10.7554/eLife.41720.
2018
v-SNARE function in chromaffin cells.
Pflugers Arch. 2018 Jan;470(1):169-180. doi: 10.1007/s00424-017-2066-z.
A mechanism for exocytotic arrest by the Complexin C-terminus.
Elife. 2018 Jul 25;7:e38981. doi: 10.7554/eLife.38981.
2016
Dhara M, Yarzagaray A, Makke M, Schindeldecker B, Schwarz Y, Shaaban A, Sharma S, Böckmann RA, Lindau M, Mohrmann R, Bruns D.
v-SNARE transmembrane domains function as catalysts for vesicle fusion.
Elife. 2016 Jun 25;5:e17571. doi: 10.7554/eLife.17571.
2015
Mohrmann R, Dhara M, Bruns D.
Complexins: small but capable.
Cell Mol Life Sci. 2015 Nov;72(22):4221-35. doi: 10.1007/s00018-015-1998-8. Epub 2015 Aug 6.
2014
Dhara M, Yarzagaray A, Schwarz Y, Dutta S, Grabner C, Moghadam PK, Bost A, Schirra C, Rettig J, Reim K, Brose N, Mohrmann R, Bruns D.
Complexin synchronizes primed vesicle exocytosis and regulates fusion pore dynamics.
J Cell Biol. 2014 Mar 31;204(7):1123-40. doi: 10.1083/jcb.201311085.
Weber JP, Toft-Bertelsen TL, Mohrmann R, Delgado-Martinez I, Sørensen JB.
Synaptotagmin-7 is an asynchronous calcium sensor for synaptic transmission in neurons expressing SNAP-23.
PLoS One. 2014 Nov 25;9(11):e114033. doi: 10.1371/journal.pone.0114033
2013
Borisovska M, Schwarz YN, Dhara M, Yarzagaray A, Hugo S, Narzi D, Siu SW, Kesavan J, Mohrmann R, Böckmann RA, Bruns D.
Membrane-proximal tryptophans of synaptobrevin II stabilize priming of secretory vesicles.
J Neurosci. 2012 Nov 7;32(45):15983-97. doi: 10.1523/JNEUROSCI.6282-11.2012.
Mohrmann R, de Wit H, Connell E, Pinheiro PS, Leese C, Bruns D, Davletov B, Verhage M, Sørensen JB.
Synaptotagmin interaction with SNAP-25 governs vesicle docking, priming, and fusion triggering.
J Neurosci. 2013 Sep 4;33(36):14417-30. doi: 10.1523/JNEUROSCI.1236-13.2013.
2012
Mohrmann R, Sørensen JB.
SNARE requirements en route to exocytosis: from many to few.
J Mol Neurosci. 2012 Oct;48(2):387-94. doi: 10.1007/s12031-012-9744-2.
2010
Mohrmann R, de Wit H, Verhage M, Neher E, Sørensen JB.
Fast vesicle fusion in living cells requires at least three SNARE complexes.
Science. 2010 Oct 22;330(6003):502-5. doi: 10.1126/science.1193134. Epub 2010 Sep 16.